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traditional and alternative medicine for children ages 0-21.
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|Early Allergen Exposure Cuts Wheeze Risk|
Early Allergen Exposure Cuts Wheeze Risk
The URECA cohort has been followed since birth, with researchers regularly collecting samples of house dust from their homes.
The full cohort was evaluated when the children were 3 to test the notion that high exposures to allergens, such as those associated with cockroaches and mice, are linked to allergic sensitization and recurrent wheezing.
Within the cohort, Wood and colleagues conducted a nested case control study to see if early life exposure to microbes in the house dust was also linked to allergic sensitization and wheezing.
Specifically, they annually measured allergen-specific IgE for milk, egg, peanut, and German cockroach. When the children were 2 and 3, they also looked for specific IgE for dust mites, dog, cat, mouse, and Alternaria, a fungal genus.
And, when children were 33 months old, the researchers performed skin prick testing for 14 common indoor and outdoor allergens.
In the case-control study, involving 104 children, the researchers found a parallel protective effect for some bacteria in house dust, again when exposure was in the first year of life.
The children involved turned out to be roughly evenly divided at age 3 into four categories, those with wheeze alone, atopy alone, both, or neither.
Wood and colleagues found that differences in house-dust bacterial content in the first year were associated with atopy and atopic wheeze.
Relative bacterial richness -- the number of bacterial types in each sample, was significantly different (at P<0.02) among the groups and was lower in first-year dust samples from the groups with atopy and atopy/wheeze, compared with children who had neither.
Finally, Wood and colleagues found, children without atopy or wheeze were more likely to have been exposed to high levels of both allergens and microbes in the first year of life.
|Aspartame Side Effects|
|Before You Tidy Up After Your Pet, Consider This New Discovery|
By Dr. Becker
In the last dozen years, numerous studies have emerged that suggest children who grow up with a dog or cat are less likely to develop allergies, asthma, and respiratory and ear infections than children without pets.